Publications

Jahng, J., Brocious, J., Fishman, D., Yampolsky, S., Nowak, D., Huang, F., Apkarian, V., Wickramasinghe, H., Potma, E.
We perform time-resolved pump-probe microscopy measurements by recording the local force between a sharp tip and the photo-excited sample as a readout mechanism for the material’s nonlinear polarization. We show that the photo-induced force is sensitive to the same excited state dynamics as measured in...
Jahng, J., Brocious, J., Fishman, D., Huang, F., Li, X., Tamma, V., Wickramasinghe, H., Potma, E.
A theoretical and experimental analysis of the dominant forces measured in photoinduced force microscopy is presented. It is shown that when operated in the noncontact and soft-contact modes, the microscope is sensitive to the optically induced gradient force (Fg) and the scattering force (Fsc). The...
Han, SW., Morita, K., Simona, P., Kihara, T., Miyake, J., Banu, M., Adachi, T.
Actin filaments play essential roles in many kinds of cellular functions by interacting with hundreds of actin binding proteins. Here we probe the interaction between actin filament and a binding protein, α-actinin, using an atomic force microscopy (AFM) and dynamic force spectroscopy (DFS). The distribution...
Reisch, A., Didier, P., Richert, L., Oncul, S., Arntz, Y., Mély, Y., Klymchenko, AS.
The current challenge in the field of fluorescent nanoparticles (NPs) for bioimaging is to achieve extreme brightness and external control of their emission using biodegradable materials. Here we propose a new concept of fluorescent polymer NPs, doped with ionic liquid-like salts of a cationic dye...
Sheridan, KJ., Dolan, SK., Doyle, S.
Non-ribosomal peptide (NRP) synthesis in fungi requires a ready supply of proteogenic and non-proteogenic amino acids which are subsequently incorporated into the nascent NRP via a thiotemplate mechanism catalyzed by NRP synthetases. Substrate amino acids can be modified prior to or during incorporation into the...